About the Pathology Core
The Pathology Core Laboratory at the Joseph Stokes Jr. Research Institute provides basic histopathology, research immunohistochemistry, tissue microarray, and laser capture microdissection services to researchers at Children's Hospital and within the surrounding academic community. We are located on the 7th Floor of the Leonard and Madlyn Abramson Pediatric Research Center in room 706. Daniel Martinez (267-426-5635, martinezd@email.chop.edu) is the Lab Manager and can address all questions regarding basic histopathology, research immunohistochemistry, tissue microarray and laser capture microdissection. Dr. Alexander R. Judkins, M.D. is the Faculty Director.
The Pathology Core Laboratory unites three core components in a single core facility: histopathology, tissue microarray and laser capture microdissection. The core offers a full range of histopathology services including tissue processing, embedding, and cutting, for both paraffin and frozen tissue. We also perform most standard stains as well as immunohistochemistry, antibody workup, fluorescence, in situ hybridization and TUNEL. Tissue microarrays can be constructed using a Beacher Arrayer. Sophisticated imaging instrumentation is available for virtual microscopy (ScanScope from Aperio) and image analysis (Imag ProPlus, Volocity). Specialized software is available to image and analyze tissue microarrays, and to manage and store array data.