For all inquiries regarding the practice-based research network (PBRN), please contact:

General Public Resources (for learning more about the benefits of PBRN-mediated research):

Practice-Based Research Networks: The Laboratories of Primary Care Research: This manuscript is an excellent review of practice-based research networks (PBRNs), their historical development, and their contribution over the years to healthcare practice.

Clinician-based Involvement in Clinical Research: Primary Care Practice-based Research Networks: This presentation was made at a steering committee meeting for "Building Collaboration for Clinical Research Networks." The presentation provides a good overview of the growth of PBRNs over the past few years and provides solid examples of some relevant research findings that would have been unobtainable using traditional research trials.

PBRN Industry Resources:

AHRQ Support for Primary Care Practice-Based Research Networks: The Agency for Healthcare and Research Quality (AHRQ) contracts many research studies to its members, such as the Hospital's PeRC. AHRQ's Web site describes the rolf of PBRNs role and provides a variety of information and links.

Primary Care Practice-Based Research Networks Resource Center: AHRQ and the Robert Wood Johnson Foundation, in conjunction with Indiana University School of Medicine, offer the PBRN Resource Center, which provides support resources for PBRN initiatives.

Federation of Practice Based Research Networks: The Federation of Practice Based Research Networks offers a starting point to begin learning about the many different types of PBRN's in the United States.

For Research Professionals:

The March-April 2007 issue of the Journal of the American Board of Family Medicine (Vol. 20, Issue 2) focused on practice-based research. The issue highlights examples of the potential benefits of PBRNs, such as the network employed by PeRC. All the articles listed here are open access:

Fagnan LJ, Morris C, Shipman SA, Holub J, King A, Angier H. Characterizing a practice-based research network: Oregon Rural Practice-Based Research Network (ORPRN) survey tools. J Am Board Fam Med. Mar-Apr 2007;20(2):204-219.

Graham DG, Spano MS, Manning B. The IRB challenge for practice-based research: strategies of the American Academy of Family Physicians National Research Network (AAFP NRN). J Am Board Fam Med. Mar-Apr 2007;20(2):181-187.

Graham DG, Spano MS, Stewart TV, Staton EW, Meers A, Pace WD. Strategies for planning and launching PBRN research studies: a project of the Academy of Family Physicians National Research Network (AAFP NRN). J Am Board Fam Med. Mar-Apr 2007;20(2):220-228.

Kho A, Zafar A, Tierney W. Information technology in PBRNs: the Indiana University Medical Group Research Network (IUMG ResNet) experience. J Am Board Fam Med. Mar-Apr 2007;20(2):196-203.

Nagykaldi Z, Mold JW. The role of health information technology in the translation of research into practice: an Oklahoma Physicians Resource/Research Network (OKPRN) study. J Am Board Fam Med. Mar-Apr 2007;20(2):188-195.

Peer-Reviewed Publications:

Pinto-Martin J, Levy SE. Early diagnosis of autism spectrum disorders. Curr Treat Options Neurol. 2004 Sep;6(5):391-400

Guevara JP, Feudtner C, Romer D, Power T, Eiraldi R, Nihtianova S, Rosales A, Ohene-Frempong J, Schwarz DF. Fragmented care for inner-city minority children with attention-deficit/hyperactivity disorder. Pediatrics. 2005 Oct;116(4):e512-7

Coffin SE, Elser J, Marchant C, Sawyer M, Pollara B, Fayorsey R, Nelson L, Lawley D, Goveia M, Stek J, Hille D, DiNubile MJ. Impact of acute rotavirus gastroenteritis on pediatric outpatient practices in the United States. Pediatr Infect Dis J. 2006 Jul;25(7):584-9

Fiks, AG, Alessandrini, EA, Luberti, AA, Ostapenko, S., Zhang, X., and Silber, JH. Identifying factors predicting immunization delay for children followed in an urban primary care network using an electronic health record. Pediatrics. 2006 Dec;118(6):e1680-6

Conway, PH, Cnaan, A, Zaoutis, T, Henry, BV, Grundmeier, RW, Keren, R. Recurrent urinary tract infections in children: Risk factors and association with prophylactic antimicrobials. JAMA. 2007 Jul;298(2):179-86

Binns HJ, Campbell C, Brown, MJ. Interpreting and managing blood lead levels of less than 10ug/dL in children and reducing childhood exposure to lead: recommendations of the Centers for Disease Control and Prevention Advisory Committee on Childhood Lead Poisoning Prevention. Pediatrics. 2007 Nov;120;e1285-e1298

Myerburg RJ, Vetter VL. Electrocardiograms should be included in preparticipation screening of athletes. Circulation. 2007 Nov;116:2616-2626 8. Fiks, AG, Grundmeier, RW, Biggs, LM, Localio, AR, Alessandrini, EA. Impact of clinical alerts within an electronic health record on routine childhood immunization in an urban pediatric population. Pediatrics. 2007 Nov;120(4):707-14

Grundmeier, RW, Swietlik, M, Bell, LM. Research subject enrollment by primary care pediatricians using an electronic health record. Proc AMIA Symp. 2007;:pending publication.

Power, TJ, Mautone, JA, Manz, PH, Frye, L, Blum, NJ. Managing attention-deficit/hyperactivity disorder in primary care: A systematic analysis of roles and challenges. Pediatrics. 2008 Jan;121;e65-e72

Meltzer, LJ. Brief report: Sleep in Parents of Children with Autism Spectrum Disorders. Journal of Pediatric Psychology. 2008 Feb; doi;10.1093/jpepsy/jsn005; 1-7.

PeRC Abstracts and Posters:

Coffin S, Spandorfer P, Clark HF, Lawley D, Davis L, Grundmeier RW, Luberti A. Burden of Illness Attributable to Rotavirus Among Non-Hospitalized Children. PAS Poster Presentation: Ambulatory Pediatric Association 2004 Annual Meeting, San Francisco, CA. May 2004:1947

Fiks AG, Luberti AA, Ostpanko O, Zhang X, Silber JH. Identifying Factors Predicting Immunization Delay for Children Followed in an Urban Primary Care Network Using an Electronic Medical Record (EMR). Poster Presentation: Ambulatory Pediatric Association 2004 Annual Meeting, San Francisco, CA. May 2004:1947

Grundmeier RW, Luberti AA, Coffin SE, Langlotz CP, Johnson KB. Structured vs. Unstructured Data Entry: Measuring Attitudes and Comparing Documentation Completeness in Primary Care Pediatrics. PAS Poster Presentation: Ambulatory Pediatric Association 2004 Annual Meeting, San Francisco, CA. May 2004:1270.

Alessandrini E, Nadel F, Alpern E, Fiks A, Shea J. Effects of a Primary Care-Based Educational Intervention on Parental Knowledge and Health Service Use for Common, Minor Childhood Illnesses. Poster Presentation: Ambulatory Pediatric Association 2005 Annual Meeting, Washington, DC. PAS May 2005:57:2817.

Coffin S, Elser J, Marchant C, Fayorsey R, Sawyer M, Pollara B, Nelson L, Goveia M, Stek J, Hille D, DiNubile M. Impact of rotavirus gastroenteritis in the pediatric outpatient setting. Pediatric Academic Society. Washington, D.C. May, 2005. 101:1899

Fiks, AG, Grundmeier, R, Biggs, L, Alessandrini, A. Clinical Alerts in an Electronic Health Record (EHR) Significantly Reduce Missed Opportunities for Immunization in an Urban Pediatric Population. Poster Symposium Presentation: Ambulatory Pediatric Association 2005 Annual Meeting, Washington, DC. PAS May 2005:57:868.

Fiks, AG, Grundmeier, R, Biggs, L, Alessandrini, A. Assessing the Impact of Withholding the Fourth Dose of DTaP Until Children Reach Fifteen Months of Age on Immunization Rates in an Urban Pediatric Population. Poster Presentation: Ambulatory Pediatric Association 2005 Annual Meeting, Washington, DC. PAS May 2005:57:1687.

Perella, D, Fiks A, Spain, CV, Robinson D, Gargiullo P, Watson, B, Heath K, Pletcher, J, Forke, C, Schmid. Validity of Reported Varicella History as a Marker for Varicella-Zoster Virus (VZV) Immunity Among Different Age Groups. Poster Presentation: Ambulatory Pediatric Association 2005 Annual Meeting, Washington, DC. PAS May 2005:57:692.

Kassam-Adams, N. Integrating Traumatic Stress Prevention and Treatment into Acute Pediatric Medical Care. Paper presented at the 9th European Conference on Traumatic Stress, Stockholm, Sweden, June 2005.

Crossette JM, Grundmeier, RW. Facilitating patient safety and quality initiatives with an Electronic Health Record in a pediatric primary care setting. Presented at the 2005 Patient Safety and Health Information Technology Conference, Washington, DC, June 2005.

Bell LM, Grundmeier R, Crossette J. Creating a Practice Based Research Network (PBRN): Using an EHR as a resource for TRIP initiatives. Presented at the 2005 TRIP Conference, Sponsored by AHRQ, Washington, DC, July 2005.

Kassam-Adams, N. Preventing PTSD after pediatric illness and injury. Presented at the National Conference of the American Academy of Pediatrics (AAP), Washington, DC, October, 2005.

Kassam-Adams, N., Marks, A., Winston, F. A stepped approach to secondary prevention of PTSD in injured children. Paper presented at the 21st Annual Meeting of the International Society of Traumatic Stress Studies, Toronto, ON, November, 2005.

Marks, A., Kassam-Adams, N., Winston, F. Preventive intervention: Addressing traumatic stress in primary care. Paper presented at the 21st Annual Meeting of the International Society of Traumatic Stress Studies, Toronto, ON, November, 2005.

Friedlaender EY, Posner JC, Hillier A, Garcia-Espana JF, Branas CC, Winston, FK. Substandard Housing and Risk of Injury in Children. Poster Symposium Presentation: Ambulatory Pediatric Association 2006 Annual Meeting, San Francisco. PAS May 2006: 2912.432.

Gerdes M, Grundmeier RW, Haecker T. Developmental Screening in an Electronic Health Record. PAS Poster Presentation: Ambulatory Pediatric Association 2006 Annual Meeting, San Francisco, CA. May 2006:2920.481

Grimberg A, Grundmeier RW, Ramos MO, Pati S, Cucchiara AJ. Poor Growth Is Mostly Over-Looked in Urban, Largely Minority, Underserved Pediatric Practices. PAS Poster Presentation: Ambulatory Pediatric Association 2006 Annual Meeting, San Francisco, CA. May 2006:2915.453

Grundmeier RW, Lehmann C, Li S, Weinberg S, Adams W, Shiffman R. Using Electronic Health Records for Pediatric Research and Quality Improvement. PAS Educational Workshop: Ambulatory Pediatric Association 2006 Annual Meeting, San Francisco, CA. May 2006:5224

Perella D, Spain CV, Fiks AG, et. al. “Screening Young Adolescents for Varicella Vaccination: Parental Recall Versus Self-Reported Varicella History,” Poster Symposium Presentation: Ambulatory Pediatric Association 2006 Annual Meeting, San Francisco. PAS May 2006: 2747.9.

Zorc JJ, Bryant-Stephens T, Grundmeier RW. Use of an Asthma Management Plan in an Electronic Health Record. PAS Poster Presentation: Ambulatory Pediatric Association 2006 Annual Meeting, San Francisco, CA. May 2006:4881.425.

Arbogast KB, Houseknecht E, Marigowda S, Mong DA. Anthropometric Measures of Pediatric Seat Belt Fit. Abstract presented at the 2006 World Congress of Biomechanics, July 29-Aug 4, 2006.

Power, T. J., Blum, N. J., Mautone, J. A., Frye, L. Providing ADHD services in primary care: The perspective of primary care physicians. Presented at the annual meeting of the Society for Developmental and Behavioral Pediatrics, Philadelphia, PA, September 2006.

Magge, SN, Katz, LL, Behr, M, Stettler, N. High Risk for Abnormal Glucose Tolerance in Overweight Siblings of Children with Type 2 Diabetes Mellitus. Poster Presentation. Conference on Cardiovascular Disease Epidemiology and Prevention in association with Council on Nutrition, Physical Activity, and Metabolism, American Heart Association, Orlando, FL. February, 2007.

Magge, SN. JDRG Fellows’ Research Forum. Poster Presentation. Chantilly, VA. March, 2007.

Fiks, AG, Hunter, KF, Grundmeier, RW, Localio, AR, Bryant-Stephens, T, Luberti, AA, Bell, LM, Alessandrini, EA, “Impact of Primary Care Clinical Alerts on Influenza Vaccination for Children and Adolescents with Asthma,” Accepted for Poster Symposium Presentation at the Pediatric Academic Societies: 2008 Annual Meeting, Honolulu, Hawaii, May 3, 2008.