Bioinformatics Core
The Bioinformatics Core (BiC) facility is a service unit of the Center for Biomedical Informatics (CBMi) and the Joseph Stokes Jr. Research Institute. Our objective is to develop and apply strong bioinformatics capabilities to enable, enhance, and empower research, discovery, and clinical application for researchers and staff at The Children's Hospital of Philadelphia.
Upcoming Events
Healthcare Informatics Colloquium
12:00 PM – 1:00 PM, December 10, 2009: Wood Club B
Designing a Health Information Technology Evaluation
Paulina Sockolow, DrPhD, MBA
Healthcare Informatics Colloquium
12:00 PM – 1:00 PM, January 14, 2010: Wood Club B
Unlocking the Electronic Health Record to Accelerate Clinical Effectiveness Research
Ron Keren, MD
Healthcare Informatics Colloquium
12:00 PM – 1:00 PM, February 3, 2010: Main Hospital 1NW 17&18
Web 2.0
Fran Cornelius, PhD, MSN, CNE, RN-C
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BiC News
CHOP CNV Database Featured on OpenHelix Blog
November 09, 2009
New Grant Funded Research:Regulation of Foxp3 Function
July 21, 2009
New Grant Funded Research:Genetic Modifiers of Liver Disease Severity in Alagille Syndrome
July 21, 2009
New Grant Funded Research:Islet Dysregulation in Infants with Congenital Hyperinsulinism
July 21, 2009
New Publication: BiC Leads Research on High-Resolution Mapping and Analysis of Copy Number Variations in the Human Genome
July 10, 2009
New Publication: BiC Leads Research on Rare Structural Variants Found in Attention-Deficit Hyperactivity Disorder
June 23, 2009
The Bioinformatics Core Helped to Understand Why the Flu May Turn Deadly
May 27, 2009
More...
Services
General Services:
- Study design
- Data quality assessments
- Consultation
Expression Microarray Analysis:
- Normalization and summarization
- Significance testing
- Predictive modeling and classification
- Pathway and ontology enrichment
- Other researcher-directed analyses
Copy Number Variation Genotyping
- Identification of copy number regions
- Linkage to phenotypes
- Funtional analysis of variant regions
Nucleic Acid and Protein Sequence Analysis
Scripting and Coding Services
Bioinformatics Training
All services provided using one of two cost recovery mechanisms:
- Percent effort on grants as part of research team
- Hourly fee-based service
Contact us for access to any of these services, a free initial consultation, or to ask questions.